2014년 11월 25일 화요일

on the Use of the Circulation of the Blood 5

on the Use of the Circulation of the Blood 5


With the calm quantitative account which a reader of Hales'
"Statical Essays" will find given by that clergyman of his
epoch-making physical experiments upon the blood-pressure, it is
interesting to compare the following vivid qualitative recital of
inferences made from surgical observations by his great predecessor.
Harvey says:--

     "Moreover, whoever shall have seen and thought upon the amount
     of difficulty and exertion with which the blood is stanched by
     compression, ligatures, or various appliances, when it leaps
     impetuously out of a petty artery, even the smallest, which
     has been cut or torn in two; and shall have seen or thought
     upon the amount of force with which the blood, as though thrown
     out from a syringe, flings off and drives before it the whole
     of the appliances, or traverses them--that man will hardly
     believe it probable, I think, that any of the blood can pass
     backward against so great an impulse and influx of the entering
     blood, unless from a point whence it is driven back with equal
     force."[254]

Harvey rightly discountenanced the ancient idea of direct
anastomoses between the mouths of veins and the mouths of
arteries, as opposed to fine and multiplied communications. In
some situations, however, he admitted that ampler communications
exist comparable to such anastomoses; and it throws light upon
his state of mind as to the movement of the blood that, despite
his recognition of the very forcible exit of the blood from the
arteries, he suggested in his old age that in the cases aforesaid
regurgitation from vein to artery is guarded against by a valvular
arrangement, the terminal part of the artery traversing the wall of
the vein obliquely, as the ureter traverses the wall of the bladder
and as the biliary duct traverses the wall of the duodenum.[255]
We should not forget that in his day the capillary vessels, the
existence of the corpuscles, and the chemistry of the blood were
still unknown; so that the passage into the veins of the mysterious
hot vital liquid through the "porosities" of the parts might
naturally present itself to his mind in a way very strange to us. He
tells us this:--

     "The blood does not take its course through the looser texture
     of flesh and parenchyma in the same way as through the more
     compact consistency of tendinous parts. Indeed, the thinner and
     purer and more spirituous part passes through more quickly; the
     thicker, more earthy, ill-composed[256] part tarries longer and
     is rejected."[257]

After more than twenty years of the comment and criticism, called
forth by his treatise of 1628, he said to Riolanus:--

     "As to whether the moving blood be attracted, or impelled, or
     move itself by virtue of its own intrinsic nature, enough has
     been said in my little book on the motion of the heart and
     blood."[258]

Yet about two years after the Exercises to Riolanus, Harvey, in
writing a private letter, judged it necessary to accentuate, as
follows, his denial that forces of attraction really play the part
in physiology which the ancients had conceded to them. Speaking of
the impulsion of the blood through the arteries, he says:--

     "Indeed, the passage of the blood into the veins is brought
     about by that impulsion and not by any dilatation of the veins
     whereby, like bellows, they draw in the blood."[259]

But, despite the foregoing utterances and other such, his statements
are sometimes vague and sometimes quite unexpected, regarding the
nature of the movement of the blood in the veins. Indeed, in 1628 he
speaks quite as a disciple of Aristotle. He says regarding the flow
in the arteries:--

     "For this distribution and movement of the blood there is need
     of impetus and violence and of an impeller such as the heart.
     Partly because the blood readily concentrates and gathers
     together of itself--toward its seat of origin, as it were,[260]
     or as a part to the whole, or as a drop of the water sprinkled
     upon a table to the mass thereof--as the blood habitually
     and very speedily does from slight causes, from cold, fear,
     horror, and other causes of this sort; partly, also, because
     the blood is pressed out of the capillary veins into the small
     branches and thence into the greater by the movements of the
     limbs and the compression of the muscles; the blood is more
     disposed and prone to move from the circumference on the center
     than the other way, even supposing no valves to be present as
     a hindrance. In order, therefore, to relinquish its seat of
     origin, and enter constricted and colder places, and move in
     opposition to its bent,[261] the blood has need not only of
     violence but of an impeller, such as is the heart alone, and
     after the fashion described already."[262]

This picture of the blood hesitating to leave its warm cardiac
birthplace for the chill regions of the periphery, but very ready to
return, has a tone far from hydraulic, but may so much the better
prepare us for the view, made public by Harvey in his old age, that
the blood is the primal seat of the soul itself. Except in the light
of the foregoing passage the following words would be quite obscure.
He says that the auricles

     "are filled as being the storehouse and reservoir[263] of the
     blood, the blood turning of itself and compressed toward the
     center by the movement of the veins."[264]

With due allowance for the use of modes of expression no longer
familiar we find Harvey in 1649 handling the venous flow with
no very modern touch, in the following passage--a passage which
also reminds us that not till twelve years later, four years
after Harvey's death, did Malpighi announce his discovery of the
capillary blood-vessels in the lung of the frog.[265] Harvey says to
Riolanus:--

     "The arteries are never depleted except into the veins or the
     porosities of the parts, but are continually stuffed full by the
     pulse of the heart; but in the vena cava and the circulatory
     vessels, into which the blood glides at a quick pace and hastens
     toward the heart, there would be the greatest scarcity of blood,
     did not all the parts incessantly pour out again the blood
     poured into them. Add, also, that the impetus of the blood which
     is urged and driven at every pulsation into all parts of the
     second and third regions, forces the blood contained therein
     from the porosities into the little veins and from the branches
     into the larger vessels; this being effected also by the motion
     and compression of the surrounding parts; for contents are
     squeezed out of whatever contains them, when it is compressed
     and narrowed. So by the movements of the muscles and limbs the
     venous branches which creep on between are pressed upon and
     narrowed, and push on the blood from the lesser toward the
     greater."[266]

A similar touch of vagueness is perceptible when the venous flow is
dealt with by Harvey in that very same resume of the circulation
which seats the underlying cause of the pulse in the hot blood
of the vena cava close to the auricle. In that resume he says to
Riolanus:--

     "I assert, further, that the blood in the veins courses always
     and everywhere from the lesser into the greater and hastens from
     all parts toward the heart; whence I gather that the amount,
     continuously sent into the arteries, which the arteries have
     received is transferred through the veins, and at length returns
     and flows back whence it first was impelled; and that in this
     wise the blood is moved in a circle in flux and reflux by the
     heart, by an impulsion the impetus of which forces the blood
     through all the arterial filaments; and that afterward in a
     continuous flow from all parts it goes back through the veins,
     one after another, by which it is absorbed, drained away, and
     transported."[267]

As to the flow in the lungs Harvey says in the treatise of 1628:--

     "It being the will of nature that the blood itself be strained
     through the lungs, she was obliged to superadd the right
     ventricle, in order that by the beat thereof the blood might be
     driven through the lungs themselves, out of the vena cava into
     the cavity of the left ventricle."[268]

We have already found Harvey saying to Riolanus, in regard to
the pulmonary transit, that the blood within the branches of the
arterial vein

     "cannot now go back in opposition to the sigmoid valve, while
     at the same time the lungs are widened and enlarged and then
     narrowed, by inspiration and expiration, and with the lungs
     their vessels also, and offer to the blood aforesaid a path and
     transit into the venous artery."[269]

More than thirty-two years earlier Harvey had written in his
note-book the following words:--

     "N.B. The lungs by their movement in subsiding propel blood from
     the arterial vein into the venous artery and thence into the
     left auricle."[270]

When we review and ponder the foregoing delineations of the
character of the movement of the blood, we may cease to wonder
that Harvey did not recognize the simple hydraulic cause of the
distention of the right auricle and felt obliged to seek a more
recondite explanation thereof, finding this in an Aristotelian
expansion of the hot blood.




CHAPTER IX

THE BLOOD THE SEAT OF THE SOUL


No doctrine of Harvey sounds stranger to a biologist of to-day than
his doctrine that the blood is the seat of the soul; nor does any
other belief of the great discoverer reveal him more clearly to be a
link between the old and the new; not simply an innovator who fixed
a gulf between them. We have heard him explicitly deny in his old
age the Aristotelian doctrine that the heart "is endowed with soul."
We have seen that thirty-five years earlier he had jotted down in
his note-book these words: "The soul is in the blood."[271] Let us
study him now as he lays stress, not merely on the primacy of the
blood, but on its psychological endowments.

Thirteen years before the date of Harvey's note-book Shakspere's
play of "Hamlet" had appeared in print; in which the prince speaks
thus of following his father's ghost:--

          "Why, what should be the fear?
    I do not set my life at a pin's fee;
    And, for my soul, what can it do to that,
    Being a thing immortal as itself?"[272]

It has been foreshadowed that for Harvey, the graduate of
Cambridge and of Padua, the physician of the Renaissance, the word
"_anima_"--"soul"--did not simply mean the immortal part of man,
as for Hamlet, but was equivalent to the "_psyche_" of ancient
philosophy. In order, therefore, readily to follow Harvey's thought
at this juncture, we must first, like him, go to the fountain head;
for only sayings of Aristotle can give us a sufficient clue to what
he, and after him Harvey, meant by "soul."

Aristotle says in his treatise On Soul:--

     "Some natural bodies have life and some have not. By life we
     mean the being nourished, and growing, and decaying, of oneself."

In the same treatise he says further:--

     "The soul is that by which primarily we are alive, and
     display sensation and intellect; ... but it is not matter and
     substratum."

Again he says:--

     "Were the eye an animal, vision would be the soul thereof; for
     reason indicates that vision is the essence of the eye.[273] The
     eye in its turn is the material [basis] of vision; which latter
     failing, the eye is not an eye except in name, like an eye of
     stone or in a drawing."

The doctrines of the foregoing three passages are developed and made
more explicit in the following, still from the treatise On Soul:--

     "It is the presence of life, we say, which makes the difference
     between that which has soul and that which has not. To amplify
     regarding life: we call anything alive which possesses even a
     single one of the following: intellect, sensation, motion and
     rest in space, and also the motion[274] involved in nutrition,
     and both decay and growth. Therefore, even all the plants are
     held to be alive."

A few lines further on Aristotle says, speaking of the power or
faculty[275] of taking nourishment:--

     "This can exist without the others, but not the other faculties
     without this, in mortal beings. The aforesaid is clear in the
     case of plants; for they possess no other faculty of the soul.
     To this faculty then life owes its origin in living things; but
     the being an animal owes its origin primarily to sensation;
     for beings that neither move nor change their place but yet
     possess sensation, we call animals and not merely living things.
     The primary sense, which exists in all, is touch; and just as
     the nutritive faculty can exist without touch or sensation of
     any kind, so can touch exist without the other senses. The
     "nutritive" is our term for such part of the soul as is shared
     even by plants, all animals, however, evidently possessing the
     sense of touch. The cause of the presence of each of the two
     aforesaid shall be told later. Now let us only go so far as to
     say that the soul is the source of the [faculties] aforesaid,
     and is defined by means of them, to wit: the nutritive, the
     sensory, the intellectual, the motor.[276] As to whether each of
     these is a soul or is a part of the soul; and if a part, whether
     in the sense that it is only separable by reasoning,[277] or
     locally as well--as to some of these points, it is not hard to
     see our way, but some present difficulties."[278]

If we turn to Aristotle's treatise On Generation we find him dealing
with the relations of the body to the nutritive soul, in virtue
whereof the body is alive; with its relations to the sensory soul,
in virtue whereof it is an animal body; and, finally, in man with
its relations to the intellectual soul. Of these three kinds of
soul or parts of the soul, he concludes, the mind "is alone divine;
for in the working thereof no bodily working is involved."[279]
Only soul of this divine quality does he admit to be separable from
body.[280]

The master has spoken. Now let the great pupil speak. In the last
Exercise but one of his treatise On Generation, Harvey says,
referring to the blood:--

     "It assuredly contains the soul first and foremost, not only
     the nutritive, but the sensory soul as well, and the motor. The
     blood penetrates in all directions and is present everywhere;
     if it be taken away, the soul itself is made away with
     also and at once; so that the blood would seem to be wholly
     indistinguishable from the soul or, at least, should be reckoned
     the substance of which the soul is the activity. The soul I aver
     to be such that neither is it body at all, nor yet entirely
     without body, but comes in part from without, in part is born
     on the premises,[281] and in a manner is part of the body;
     in a manner, however, is the origin and cause of everything
     within the body of an animal, certainly of nutrition, sense,
     and motion, and hence, in like manner, of life and death; for
     whatsoever is nourished, that same is living, and _vice versa_.
     So, likewise, whatsoever is nourished abundantly, increases; but
     whatsoever too sparingly, dwindles; and whatsoever is nourished
     perfectly, keeps its health; whatsoever otherwise, lapses into
     disease. Therefore, as is the soul, so also is the blood to be
     reckoned the cause and author of youth and old age, of sleep
     and of waking, and even of respiration also--especially in view
     of this, that in the things of nature the first instrument
     contains within itself an internal moving cause. Therefore, it
     comes to the same whether one say that the soul and the blood,
     or the blood together with the soul, or, if preferred, the soul
     together with the blood, bring everything within an animal to
     pass."[282]

Only two years before these words were published the aged Harvey had
said the following:--

     "Nor does the blood possess vigor, faculty, reason, motion, or
     heat, as the gift of the heart."[283]

A comparison of the foregoing passages from Harvey with the
preceding passages from Aristotle makes it clear that, for Harvey,
although the soul dwells no longer in its Aristotelian seat, it is
no other than the Aristotelian soul which pervades the "principal
part" of the body, the living blood of the Harveian circulation.

What proofs does Harvey offer that the soul is in the blood? He has
offered already one weighty piece of evidence noted by many from
of old in the chase, in butchery, in sacrifice, in battle--the
evidence from fatal hæmorrhage. This had been set forth nineteen
centuries before him by one of his Hippocratic predecessors, who had
referred to the reasoning

     "used by those who say that the blood is the man; for, seeing
     men slaughtered and the blood running out of the body, they
     conclude that the blood is the soul of man."[284]

Presently Harvey himself shall tell us that in placing the soul in
the blood he is consciously reaffirming one of the most ancient of
beliefs; but he is far from basing his adhesion to it merely on such
immemorial evidence, known to all, as the result of loss of blood,
for he also adduces once more his own observations of the early
embryo of the fowl, to prove not only the primacy of the blood but
the presence of the soul therein. His testimony follows, and in
reading it one must bear carefully in mind that in Harvey's time
no clear scientific distinction had yet been worked out between
movements which imply sensation, and movements, whether reflex or
not, which do not depend upon consciousness. In his treatise On
Generation Harvey says:--

     "For my own part I am sure from numerous experiments that not
     only motion is inherent in the leaping point,--which no one
     denies--but sensation also. For you will see this point thrown
     into varied commotion and, as it were, irritated, at any touch
     whatever, even the slightest, just as sensitive bodies in
     general usually give evidence of sensation by movements proper
     to themselves. Moreover, if the injury be repeated often, the
     leaping point becomes excited and the rhythm and order of its
     pulsations disturbed. In like manner do we infer the presence
     of sensation in the so-called sensitive plant and in zoophytes,
     from the fact that when they are touched they draw themselves
     together as though taking it ill.... So there is no doubt that
     the leaping point lives, moves, and feels like an animal."[285]

In a later part of the same treatise he says:--

     "It is manifest that all motion and sensation do not proceed
     from the brain, since we plainly perceive the presence of motion
     and sensation before the brain has come into existence; what
     I have related proves that clearly sensation and motion dawn
     forthwith in the first droplet of blood in the egg, before a
     vestige of the body has been formed. Moreover, in that first
     state of the structure or constitution of the body which I have
     called the mucilaginous, before any members are discernible and
     when the brain is nothing but limpid water, if the body be only
     lightly pricked it moves, contracts, and twists itself obscurely
     like a worm or caterpillar; so that it gives clear evidence of
     sensation."[286]

In another Exercise of the same treatise he says:--

     "It is evident also from the generation of the chick, that
     whatever the source of its life or the vegetative first cause of
     it may be, this had a prior existence in the heart. Wherefore,
     if the said first cause be itself the soul of the chick, it
     stands proved likewise that this had a prior existence in the
     leaping point and the blood; seeing that we observe therein
     motion and sensation; for it moves and leaps like an animal. If,
     then, there exist in the leaping point the soul, which (as I
     have taught in my account) constructs for itself the rest of the
     body, nourishes and increases it, certainly from the heart as
     from a fount the soul flows out[287] into the entire body.

     "So, likewise, if the egg be prolific because there is a soul
     in it, or (as Aristotle would have it) the vegetative part of
     the soul, it is clearly proved that the leaping point, in other
     words the generative part endowed with soul, springs from the
     soul of the egg, for nothing is the author of itself, and that
     the soul is transferred from the egg to the leaping point, next
     to the heart, and then to the chick."[288]

In still another chapter of his treatise On Generation Harvey
says:--

     "Nor does the blood deserve to be called the original[289] part
     and the principal part, merely because in it and by it motion
     and pulsation are originated, but also because in the blood the
     psychical heat first comes into existence, the vital spirits
     are generated, and the soul itself inheres. For wherever the
     immediate and principal instrument of the vegetative faculty is
     first found, there probably the soul also is first present and
     takes its origin thence; since the soul is inseparable from the
     spirits and the innate heat....[290]

     "The life then inheres in the blood (as we read also in Holy
     Writ),[291] because therein the life and the soul are manifest
     first and fail last....[292]

     "It stands clearly proved that the blood is a generative part,
     the source of life, the first to live and the last to die, the
     primary seat of the soul; that in the blood, as in its source,
     the heat first and chiefly abounds and flourishes; and that by
     and from the blood all the other parts of the whole body are
     fostered and obtain their life by means of the influx of heat.
     Indeed, the heat which accompanies the blood floods, fosters,
     and preserves the entire body, as I have demonstrated already in
     my book on the motion of the blood."[293]

Harvey's proof that the blood is "the first to live and the last to
die," we have scanned already in an earlier chapter of this paper.
In the next chapter of his treatise On Generation he says:--

     "No heat is to be found, either innate or inflowing, other than
     the blood, to be the soul's immediate instrument."[294]

On the next page, after briefly making certain suppositions, he says
further:--

     "Why should we not affirm with equal reason that there is soul
     in the blood; and also, since the blood is the first thing
     generated, nourished, and moved, that out of the blood the soul
     is first evoked and kindled? Certainly it is the blood in which
     vegetative and sensitive workings first come to light; in which
     heat, the primary and immediate instrument of the soul, is
     innate; it is the blood which is the common bond of body and
     soul, and in which as a vehicle soul flows into all parts of the
     whole body."[295]

But no matter how far on high the blood may have been exalted by
Harvey the physician and psychologist, it is still subject to the
lancet of Harvey the clinician, the heir of Hippocrates; for in his
treatise On Generation, in the same Exercise with the foregoing
passage, occurs the following:--

     "While I assert that the seat of the soul is in the blood,
     first and foremost, I would not have the false conclusion drawn
     from this that all blood-letting is dangerous or hurtful; nor
     have it believed, as the multitude believes, that just to the
     degree that the blood is taken away does the life pass away at
     the same time, because holy scripture has placed the life in
     the blood. For it is known from everyday experience that the
     taking of blood is a wholesome aid against very many diseases
     and is chief among the universal remedies; seeing that depravity
     of the blood, or excess thereof, is at the bottom of a very
     great host of diseases; and that the timely evacuation of
     blood often brings exemption from most dangerous diseases and
     even from death itself. For just to the degree that the blood
     is taken away as our art prescribes, is an addition made to
     life and health. This very thing has been taught us by Nature,
     whom physicians set themselves to imitate; for Nature often
     makes away with the gravest affections by means of a large
     and critical evacuation by the nares, by menstruation, or by
     hæmorrhoids."[296]

Not only does Harvey affirm that "the soul is in the blood" and, as
we have seen, appeal to observation and experiment in support of
this doctrine; but he refers to those who had believed it before
him, and maintains it against Aristotle's express denial. We
have heard him testify as an observer; now let us hear him deal
historically and polemically with the doctrine in question. Quite
simply, in the final work of his old age, does the veteran tell of
the wide acclaim which at last has greeted his discovery of the
circulation--the most modern and revolutionary achievement of his
time. The contrast is startling when, in the same breath, with equal
simplicity he proceeds formally to identify his own latest view of
the significance of the circulating blood with a doctrine which had
been ancient in ancient times; a doctrine not only found in the Old
Testament, but held by Greek thinkers who were historic figures
even in the eyes of Aristotle. In his treatise On Generation Harvey
says:--

     "I see that the admirable circulation of the blood which I
     discovered long ago has proved satisfactory to nearly all, and
     that so far no one has made any objection to it which greatly
     calls for answer. Therefore, if I shall add the causes and
     uses of the circulation and reveal other secrets of the blood,
     showing how much it conduces to mortal happiness and to the
     welfare of soul as well as body, that the blood be kept pure
     and sweet by a right regimen, I truly believe that I shall do a
     work as useful and grateful to philosophers and physicians as
     it will be new; and that the following view will seem to nobody
     so improbable and absurd as it formerly seemed to Aristotle,
     viz.: that the blood, a domestic deity as it were, is the very
     soul within the body, as Critias and others thought of old;
     they 'believing that capacity for sensation is the most special
     attribute of the soul, and exists because of the nature of the
     blood.' By others again that which derives from its own nature
     the power of causing motion was held to be the soul; as Thales,
     Diogenes, Heraclitus, Alcmæon, and others believed.[297] It is
     made plain, however, by very numerous signs that both sensation
     and motion inhere in the blood in spite of Aristotle's[298]
     denial."[299]

We have noted with Harvey the doctrine of Leviticus, which still
rules the procedure of the Jewish butcher; and as we look backward
to Athens across the centuries, we find Plato putting this question
into the mouth of Socrates: "Whether it be the blood with which
we think, or air, or fire, or none of these."[300] In Hellas
this doctrine had been well known before Plato, Socrates, or the
Hippocratic writers, one of whom we have found referring to it.
The Sicilian Greek Empedocles, a philosopher and physician born at
Acragas about 495 B.C., is said to have held, long before Aristotle,
that the heart is the part formed first in the embryo;[301] and
in a line of verse which has come down to us Empedocles said: "In
the blood about man's heart is his understanding."[302] Empedocles
is reported to have held to this because in the blood "are most
perfectly blended the elements of the parts,"[303] that is, earth,
water, air, and fire.

The accomplished and wicked Athenian Critias, to whom Harvey refers,
was that chief of the Thirty Tyrants who was slain in 403 B.C., four
years before Socrates drank the hemlock and nineteen years before
the birth of Aristotle. With the opinion of "Critias and others"
Harvey, as we have seen, identifies his own view that the soul is in
the blood. They held capacity for sensation to be the mark of soul
and to be due to the nature of the blood; and Harvey's statement
of these views is a literal quotation from the second chapter of
the first book of Aristotle's treatise On Soul, which Harvey cites.
This chapter is also the source of his summary and not quite exact
reference to those other ancients who, as he avers, held spontaneous
motor power to be the mark of soul--a power which Harvey unites in
the blood with capacity for sensation.[304]

In the aforesaid chapter of Aristotle's work On Soul this
philosopher had curtly reckoned among the "cruder" thinkers those
of his predecessors who, "like Critias," had held the soul to be
blood. Harvey notes the master's condemnation, but, as we have seen,
stoutly ranges himself with the condemned ancients and affirms that
sensation is inherent in the blood despite the master's denial.
It is strange to note how the London physician seems less modern,
for the moment, than the ancient philosopher of Athens. Aristotle,
like a man of to-day, treats the blood simply as the immediate
food of the tissues, noting expressly that it has "no feeling when
touched in any animal, just as the excrement in the belly has no
feeling."[305] Harvey deals as follows with this obvious truth in
dealing with the question whether the blood can properly be reckoned
a part of the body in the technical sense. He says:--

     "At this time I will only say this: Even if we concede that
     the blood does not feel, nevertheless, it does not follow that
     it is not a part of a sensitive body and the principal part at
     that."[306]

We do not know that Aristotle ever saw or noted in the dying auricle
the "undulation" by which Harvey was so much impressed; but we
have seen that, like Harvey, Aristotle treated of the development
of the early embryo within the hen's egg and that, like Harvey,
he laid special stress upon the red "leaping point." Aristotle
concluded that the heart is the first generated living part, that
it makes and will make throughout life the blood which it contains
and distributes. In the heart he fixed the focus of the innate heat
and, knowing nothing of the nervous system, he fixed in the heart
the seat of the soul also. Harvey came to the conclusion that the
blood is the first generated living part; that it has made the heart
which contains it and which keeps it circulating and which it will
nourish throughout life, as it will the other parts. In the blood
itself he placed the innate heat and, though he knew the nervous
system, he placed in the circulating blood the seat of the soul,
which animates every part.

     "We conclude," he says, "that the blood lives and is nourished
     of itself and in no wise depends upon any other bodily part
     either prior to or more excellent than itself."[307]

Thus the rigorously proved and demonstrated circulation of the
blood was linked by its discoverer with the speculations of remote
antiquity.

As we have seen, the use of the circulation became to Harvey a
life-long subject of speculation, because this discovery had raised
questions which no man could answer before the finding of oxygen.
How obscure a problem Harvey found the functions of the blood to be,
is nowhere better indicated than where he says in his old age:--

     "So with better right one might maintain that the blood is
     equally the material of the body and its preserver, but not
     merely its food. For it is well known that in animals that
     perish of hunger, and also in men who waste away and die, there
     is abundance of blood to be found in the vessels, even after
     death."[308]

Is it the least part of Harvey's glory that his mind had cloven its
way through long-lived beliefs to a truth which he could demonstrate
but could not explain, and which seemed to other eminent men to be
no truth, because too senseless to be true?[309] When he finally
broke with the ancient master, Harvey could not be content with
sheer ignorance; and the same observations and experiments which
led him out of Aristotelian error misled him into error quite as
grave. As to the venerable doctrine regarding the seat of the soul,
which he at last embraced upon grounds now seen to be too slender,
was not this doctrine one with which the Harveian circulation
could harmonize well and which in turn could greatly glorify the
circulation? Let us pause, think, and read further.




CHAPTER X

THE BLOOD THE INNATE HEAT


The latter part of Harvey's treatise On Generation is devoted to
that of the mammal; but the treatise does not end with the end of
this subject, for from his account of generation the author turns
abruptly to append two Exercises on other topics. The first of these
two is entitled "On the Innate Heat," and the second, which is very
brief, is entitled "On the Primitive Moisture."

The Exercise On the Innate Heat is Harvey's express and polemical
contribution to this subject, which had been much discussed both
during and before his time;[310] a subject with which the famous
discoverer deals roundly by maintaining that the innate heat is
neither more nor less than the circulating blood. So the last words
as to the significance of the circulating blood which he wrote for
publication are contained in this Exercise. It begins as follows:--

     "Since mention is often made of the innate heat, I propose now,
     by way of dessert, briefly to discuss the same and the primitive
     moisture also; and this the more willingly that I see there are
     many who take the greatest delight in those names and yet, in
     my judgment, comprehend but little of the things themselves.
     Truly, there is no need to seek for any spirits distinct from
     the blood, or to bring in heat from elsewhere, or call gods
     upon the stage and load philosophy with fanciful opinions;
     for what we so commonly would fetch from the stars is born at
     home. In truth, the blood alone is the innate warmth, or the
     first-born psychical heat;[311] as is proved excellently well
     by our observations of the generation of animals, especially of
     the chick in the egg; so that it were superfluous to multiply
     entities. Indeed, there is nothing to be met with in the animal
     body prior to the blood, or more excellent; nor are the spirits
     which they distinguish from the blood to be found anywhere
     separate from it; for the very blood itself, if without spirits
     or heat, does not deserve the name of blood, but of cruor....

     "Scaliger, Fernelius, and others lay less weight on the
     extraordinary endowments of the blood and imagine other
     spirits to exist, aerial or ethereal or composed of substance
     both ethereal and elemental, constituting an innate heat more
     excellent and more divine, as it were; and these spirits
     they believe to be the soul's most immediate instrument, the
     fittest for every use. They rely especially upon this argument,
     viz.: that the blood, being composed of elements, can exert
     no activity beyond the powers of the elements or of bodies
     consisting of a mixture thereof. Therefore, they imagine a
     spirit, another innate heat, of celestial origin and nature,
     to wit: a body most simple, most subtile, most fine, most
     mobile, most swift, most clear, ethereal, and sharing in the
     quintessence. Nowhere, however, has any such gift of spirit been
     demonstrated by them, nor that the same acts beyond the powers
     of the elements, or accomplishes greater works than could the
     blood alone. As for us who use our senses to guide us in the
     scrutiny of things, nowhere have we been able to find anything
     of the kind. Furthermore, there exist no cavities destined
     for the generation or preservation of these spirits, or even
     assigned thereto by the persons aforesaid."[312]

A little farther on we read:--

     "I deem it, however, most wonderful that spirits which draw
     their origin from heaven and are adorned with such surpassing
     endowments should be nourished by our common and elemental air;
     especially seeing that their advocates hold that none of the
     elements can act beyond its own powers....[313] What need then
     is there, say I, of that foreign guest, ethereal heat, since
     all can be accomplished by the blood, even as by it; while
     from the blood the spirits cannot withdraw a hair's breadth
     without perishing? Most assuredly nowhere do they wander or
     penetrate as separate bodies without the blood. For whether it
     be said that they are generated, nourished, and increased from
     the thinner part of the blood, as some believe, or from the
     primitive moisture, as others hold; yet it is confessed that
     they are never found outside the blood but forever cleave to
     the same as to their sustenance, as flame does to oil or to
     a wick. Wherefore their tenuity, subtility, mobility, and so
     forth, confer no greater advantage than does the blood which
     they continually accompany. It follows that the blood suffices
     and is fit to be the immediate instrument of the soul, since the
     blood is present everywhere and most swiftly permeates hither
     and thither."[314]

The two opponents named by Harvey were not his contemporaries, but
worthies of the Renaissance who had written about one hundred years
before the publication of his treatise On Generation and had died
before he was born. The Italian physician Julius Cæsar Scaliger
had written learned commentaries on Aristotle, as well as other
works; and the Frenchman Jean Fernel, physician to King Henri II of
France, had taught anatomy at Paris and had been a medical writer
of importance. Each of these two authors was nearly sixty years
of age in 1543, in which memorable year were first published the
revolutionary writings of the aged astronomer Copernicus and of
the young anatomist Vesalius, in the second year after the death
of the hardy innovator Paracelsus. Such were the men against whose
doctrines Harvey was impelled in his old age to launch his vigorous
criticism, in order to clear the way for his own doctrine of the
preeminence of the blood. What can we workers of to-day make of
their opinions, which were living for Harvey but now are so deeply
buried? Test-tube and balance, telescope, spectroscope, microscope,
manometer, and the rest, have served their purpose so well since
Harvey's time that even he, one of the foremost worthies of science,
must seem merely to beat the air with words in his last message to
us, unless we can recover his standpoint. Happily he himself shall
attempt to clarify the meaning of his polemic by setting before us
certain words of Aristotle, embodying far-reaching speculations as
to body and soul in relation to the universe. Yet we shall find
these not easy to understand.

Let Harvey continue his criticism of his predecessors. He says:--

     "But while they believe that there are found in animals spirits
     and ultimate or primitive nourishment, or something else, which
     acts beyond the powers of the elements more than does the blood,
     they do not seem to have a sufficient grasp of what it may be to
     'act beyond the powers of the elements'; nor have they rightly
     interpreted the words of Aristotle where he says:[315] 'The
     virtue or potency of every soul[316] seems to be associated with
     a body[317] other than the so-called elements and more divine.'"

And a little farther on:[318]--

     "'For there exists in the semen of all [animals] that which
     makes their semen generative, the so-called heat. Yet this is
     not fire, nor any such power, but the spirits[319] included
     in the semen and in foaminess, and in the spirits the nature
     which is analogous to the element of the stars.[320] Wherefore
     fire generates no animal, nor does anything [animal] appear in
     process of formation in that, whether moist or dry, which is
     undergoing the action of fire;[321] whereas the heat of the sun
     and that of animals--not only that [which acts] through the
     semen,[322] but also, should there occur some excretion of a
     different nature[323]--even this, too, possesses a life-giving
     principle. It is patent, then, from such [facts] as these that
     the heat in animals is not fire and does not take its origin
     from fire.'[324]

     "I, too, would say the same, for my part, of the innate heat
     and the blood, to wit: that it is not fire and does not take
     its origin from fire, but is associated with another body and
     that more divine, and, therefore, does not act by reason of
     any elemental faculty; but, just as there exists in the semen
     something which makes it generative and exceeds the powers of
     the elements in building an animal--to wit, spirits, and in the
     spirits a nature analogous[325] to the element of the stars--so
     likewise in the blood there exist spirits or some power which
     acts beyond the powers of the elements, a power very conspicuous
     in the nourishing and preserving of the several parts of an
     animal; and in the spirits and blood exist a nature, yea, a
     soul, analogous to the element of the stars. It is manifest,
     therefore, that the heat in the blood of animals during life is
     not fire and does not take its origin from fire; and this is
     taught excellently well by our own observations....[326]

     "Therefore, those who assert that nothing composed of the
     elements can work beyond the powers of these, unless it be
     associated at the same time with another body and that more
     divine, and maintain, therefore, that the spirits aforesaid
     consist in part of the elements, in part of some ethereal and
     celestial substance--truly, such persons seem to me to have
     drawn their conclusions ill. For you shall find scarcely any
     elemental body which, when in action, will not exceed its own proper powers."

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